Hainan Airlines is launching a service later this month from Beijing to Khartoum in Sudan.
The twice-weekly service starts 20 November and uses an Airbus A340, says an airline spokesman.
Khartoum is the capital of Sudan, a political ally of China which has been working to develop trade ties with resource-rich Africa.
No other airlines operate on the route, according to Innovata.
Source: Air Transport Intelligence news