Air France's regional arm Hop will launch flights between Lyon and Luxembourg next year.
From 21 February, the route will be operated with ATR 42-500 turboprops six days a week, says the airline.
Flightglobal's Innovata schedules show that this will be Air France's sole service to Luxembourg, though Luxair operates flights to Paris Charles de Gaulle as a codeshare with the French flag carrier.
French regional airline Chalair Aviation serves Luxembourg from Lyon.
Source: Cirium Dashboard