Virgin Atlantic will deploy its first Airbus A350-1000 to New York John F Kennedy from London Heathrow.
It expects to receive the aircraft in "late summer".
The UK-based carrier confirmed the route choice during a launch event for the aircraft in Gatwick today, where it unveiled a new Upper Class suite as part of a complete revamp of its cabin on the incoming aircraft.
Virgin Atlantic is due to take four A350-1000s this year, and a further eight by the end of 2021.
Source: Cirium Dashboard