Senior NASA officials and aerospace industry sources say that Griffin wants to clear away entrenched bureaucracy and build a less political and more scientifically-orientated team to push ahead with the development of the Crew Exploration Vehicle (CEV) - the Space Shuttle's successor.
The sources say the officials will be officially notified today. Griffin, who is to hold meetings with his counterparts from Europe, Japan, Russia and industry representatives at the show, refuses to comment.
Griffin, is keen to progress NASA's successor to the Shuttle.
Griffin recently told a Senate oversight committee: "The shuttle is inherently flawed. It does not have an escape system for its crew. We all know that since human perfection is unattainable, sooner or later there will be another shuttle accident.
"I want to retire it before that flight can occur."
The new CEV will be used to pave the way for manned expeditions to the Moon and Mars, as well as ferrying crews to the International Space Station.
Source: Flight Daily News